Gastrointestinal, Hernia
14. Apr 2016
Abdominal wall hernias - A local manifestation of systemically impaired quality of the extracellular matrix
BACKGROUND:
Throughout life, inguinal hernia develops in approximately every fourth man, some of whom develop multiple hernias. If patients at risk of developing multiple hernias could be identified by a serologic biomarker, treatment might be able to be tailored and improved. Evidence suggests tha…
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Journal:
Authors:
- Henriksen NA,
- Mortensen JH,
- Lorentzen L,
- Ågren MS,
- Bay-Jensen AC,
- Jorgensen LN,
- Karsdal MA,
1. Feb 2015
The collagen turnover profile is altered in patients with inguinal and incisional hernia
BACKGROUND:
Disturbed metabolism in the extracellular matrix (ECM) contributes to formation of abdominal wall hernias. The aim of this study was to gain deeper insight into the ECM turnover in hernia patients by analyzing serum biomarkers specifically reflecting collagen synthesis and breakdown in …
Read the publication
Journal:
Authors:
- Henriksen NA,
- Mortensen JH,
- Sorensen LT,
- Bay-Jensen AC,
- Ågren MS,
- Jorgensen LN,
- Karsdal MA,