Respiratory System, Chronic Obstructive Pulmonary Disease, Extracellular Matrix Research
2. Dec 2019
End-product of fibrinogen is elevated in emphysematous chronic obstructive pulmonary disease and is predictive of mortality in the ECLIPSE cohort.
BACKGROUND:
Chronic obstructive pulmonary disease (COPD) is characterized by abnormal epithelial repair process that may result in intra-airway accumulation of fibrin. Given that plasma fibrinogen is the only FDA approved biomarker that predicts mortality and COPD exacerbations, we hypothesized tha…
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Journal:
Authors:
- Manon-Jensen T,
- Langholm LL,
- Ronnow SR,
- Karsdal MA,
- Tal-Singer R,
- Vestbo J,
- Leeming DJ,
- Miller BE,
- bülow Sand JM,