Hepatic System
25. Oct 2019
A Phase 1 Trial of Autologous Macrophage Therapy for Liver Cirrhosis
Therapies to reduce liver fibrosis and stimulate organ regeneration are urgently needed. We conducted a first-in-human, phase 1 dose-escalation trial of autologous macrophage therapy in nine adults with cirrhosis and a Model for End-Stage Liver Disease (MELD) score of 10-16 (ISRCTN 10368050). Groups…
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Authors:
- Moroni F,
- Dwyer BJ,
- Graham C,
- Pass C,
- Bailey L,
- Ritchie L,
- Mitchell D,
- Glover A,
- Lauire A,
- Doig S,
- Hargreaves E,
- Fraser AR,
- Turner ML,
- Cambpell JDM,
- McGowan NWA,
- Barry J,
- Moore JK,
- Hayes PC,
- Leeming DJ,
- Nielsen MJ,
- Musa K,
- Fallowfield JA,
- Forbes SJ,