Bone
11. Dec 2013
Osteoclasts are not crucial for hematopoietic stem cell maintenance in adult mice
The osteoclast is vital for establishment of normal hematopoiesis in the developing animal. However, its role for maintenance of hematopoiesis in adulthood is more controversial. To shed more light on this process, we transplanted hematopoietic stem cells from two osteopetrotic mouse models, with la…
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Authors:
- Flores C,
- Moscatelli I,
- Thudium CS,
- Gudmann NS,
- Thomsen JS,
- Brüel A,
- Karsdal MA,
- Henriksen K,
- Richter J,