Hepatic System, Gastrointestinal
12. Feb 2019
Enhanced processing of von Willebrand factor reflects disease severity and discriminates severe portal hypertension in cirrhosis
OBJECTIVES:
Portal hypertension in cirrhosis is associated with endothelial dysfunction, impaired wound healing, and decreased platelet count. Increased von Willebrand factor (VWF) formation has been suggested as a compensatory mechanism, but the role of VWF processing has not been directly assesse…
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Authors:
- Langholm LL,
- Manon-Jensen T,
- Karsdal MA,
- Bendtsen F,
- Leeming DJ,
- Møller S,