Bone
18. Oct 2005
The role of chloride channels in osteoclasts: ClC-7 as a target for osteoporosis treatment
Chloride ions play a major role in osteoclast biology and bone homeostasis. In addition to its general cellular roles, chloride is involved in the specific bone resorption activity of osteoclasts. The chloride channel ClC-7 has been shown to be mandatory for bone resorption. It is necessary for the …
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Authors:
- Schaller S,
- Henriksen K,
- Sørensen MG,
- Karsdal MA,