Bone
15. Aug 2010
Severe developmental bone phenotype in ClC-7 deficient mice
Bone development is dependent on the functionality of three essential cell types: chondrocytes, osteoclasts and osteoblasts. If any of these cell types is dysfunctional, a developmental bone phenotype can result. The bone disease osteopetrosis is caused by osteoclast dysfunction or impaired osteocla…
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Authors:
- Neutzsky-Wulff AV,
- Sims NA,
- Supanchart C,
- Kornak U,
- Felsenberg D,
- Poulton IJ,
- Martin TJ,
- Karsdal MA,
- Henriksen K,