Rheumatology, Osteoarthritis
31. Jan 2019
Molecular taxonomy of osteoarthritis for patient stratification, disease management and drug development
PURPOSE OF REVIEW:
This review focuses on the molecular taxonomy of osteoarthritis from the perspective of molecular biomarkers. We discuss how wet biochemical markers may be used to understand disease pathogenesis and progression and define molecular endotypes of osteoarthritis and how these corre…
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Journal:
Authors:
- mobasheri A,
- Van Spil WE,
- Budd E,
- Uzieliene I,
- Bernotiene E,
- Bay-Jensen AC,
- Larkin J,
- Levesque MC,
- Gualillo O,
- Henrotin Y,
Rheumatology, Osteoarthritis
16. Oct 2017
Development and use of biochemical markers in osteoarthritis: current update
PURPOSE OF REVIEW:
There is an increasing demand for noninvasive and descriptive biochemical markers (biomarkers) in osteoarthritis; for enabling early drug development (including translational research), evaluating clinical trial at an early stage and for subtyping. Purpose of the review is to rev…
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Journal:
Authors:
- Bay-Jensen AC,
- Thudium CS,
- Mobasheri A,