Respiratory System, Idiopathic Pulmonary Fibrosis, Oncology, Lung
30. Nov 2018
A serological marker of the N-terminal neoepitope generated during LOXL2 maturation is elevated in patients with cancer or idiopathic pulmonary fibrosis
OBJECTIVES:
Lysyl oxidase like 2 (LOXL2) is associated with poor prognosis in idiopathic pulmonary disease (IPF) and cancer. We developed an Enzyme-linked immunosorbent assay (ELISA) targeting the LOXL2 neo-epitope generated through the release of the signal peptide during LOXL2 maturation.
DESI…
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Authors:
- Leeming DJ,
- Willumsen N,
- Sand JM,
- Holm Nielsen S,
- Dasgupta B,
- Brodmerkel C,
- Bager CL,
- Karsdal MA,