Respiratory System, Idiopathic Pulmonary Fibrosis, Chronic Obstructive Pulmonary Disease
20. Jul 2012
Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation
BACKGROUND:
Elastin is an essential component of selected connective tissues that provides a unique physiological elasticity. Elastin may be considered a signature protein of lungs where matrix metalloprotease (MMP) -9-and -12, may be considered the signature proteases of the macrophages, which in …
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Journal:
Authors:
- Skjøt-Arkil H,
- Clausen RE,
- Nguyen QH,
- Wang Y,
- Zheng Q,
- Martinez FJ,
- Hogaboam CM,
- Han M,
- Klickstein LB,
- Larsen MR,
- Nawrocki A,
- Leeming DJ,
- Karsdal MA,