1. Sep 2014
Combined antiretroviral therapy attenuates hepatic extracellular matrix remodeling in HIV patients assessed by novel protein fingerprint markers
OBJECTIVES:
Combined antiretroviral therapy (cART) attenuates hepatic fibrosis in hepatitis C virus and HIV coinfected patients. However, the role of HIV or cART on hepatic fibrosis in HIV monoinfection is discussed controversially. During liver fibrosis, matrix metalloproteinases (MMPs) degrade ex…
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Journal:
Authors:
- Leeming DJ,
- Anadol E,
- Schierwagen R,
- Karsdal MA,
- Byrjalsen I,
- Nielsen MJ,
- Schwarzer-Zander C,
- Boesecke C,
- Bendtsen F,
- Møller S,
- Strassburg CP,
- Spengler U,
- Krag A,
- Rockstroh J,
- Trebicka JK,