Respiratory System, Chronic Obstructive Pulmonary Disease
3. May 2015
Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling
BACKGROUND:
During the pathological destruction of lung tissue, neutrophil elastase (NE) degrades elastin, one of the major constituents of lung parenchyma. However there are no non-invasive methods to quantify NE degradation of elastin. We selected specific elastin fragments generated by NE for an…
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Authors:
- Kristensen JH,
- Karsdal MA,
- Sand JM,
- Willumsen N,
- Diefenbach C,
- Svensson B,
- Hägglund P,
- Oersnes-Leeming DJ,